Relative Bioavailability Study of a Modified-Release Formulation of PF-06865571 in Healthy Adult Participants

This study is an open‐label, randomized, single‐dose, 4‐period, 4‐sequence, crossover study in a single cohort of approximately 12 healthy adult participants. The purpose of this study is to evaluate the relative bioavailability of a newly developed modified release (MR) tablet formulation of PF‐06865571 relative to an immediate release (IR) tablet formulation of PF‐06865571 under fed conditions. In addition, this study will also assess the relative bioavailability of the MR formulation under fasted conditions relative to fed conditions, in healthy adult participants. Study results will be used to determine if the new MR formulation may be suitable for use in future clinical studies with PF‐06865571. Healthy adult Japanese participants will also be enrolled in this study to support inclusion of Japanese participants in future clinical studies.