Authors
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Guangdong Provincial Second Hospital of Traditional Chinese Medicine (The Fifth Clinical Medical College of Guangzhou University of Chinese Medicine) -More
Category
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Primary study
Registry of Trials»Chinese Clinical Trial Register
Year
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2026
INTERVENTION: Trial Group:Lingnan Jiejing therapy eye acupuncture: selecting 13 points in 8 zones around the eyes. Specific procedure: using three acupuncture needles held together, starting from the lung meridian and following the sequence of the twelve meridians, puncturing points on the eyelids with combined techniques of point stimulation, scattered stimulation, and blood‐letting. Needles should be inserted quickly and superficially, with bleeding until redness appears. Left eye first, then right eye, performing 3 circles around the eye area per group, alternating between both eyes, totaling 9 groups. Basic treatment includes neurotrophic agents, drugs improving posterior circulation; median nerve electrical stimulation; 'From Yin to Yang' large meridian connecting awakening technique (acupuncture at Baihui, Neiguan, Shuigou, etc., followed by pulse stimulation and retention for 30 minutes); rehabilitation training (electric standing bed, passive movements).;Control Group:Conventional acupuncture for awakening. Main points: bilateral Fengchi, Wangu, Tianzhu, Yamen, Fugue; auxiliary points: Shuigou, Sishencong, Zhisanpin, Tiansanpin, Neiguan, Baihui, Jiquan, Weizhong, Quchi, Sanyinjiao, Zusanli. Specific procedures: Neiguan with twisting‐reducing method for 1 minute; Shuigou with twisting‐stagnation and flicking‐reducing method until lacrimation occurs; Fengchi with transcutaneous needling; Wangu, Tianzhu, Yamen, Fugue with twisting‐reducing method, straight insertion to 1 cun depth. Electroacupuncture with sparse‐dense wave stimulation; other points with conventional techniques, retaining needles for 30 seconds with twisting motion at about 200 times per minute. Retain needles for 30 minutes, once daily. Basic treatment consistent with trial group.; CONDITION: Prolonged disorders of consciousness PRIMARY OUTCOME: Change in total Coma Recovery Scale‐Revised (CRS‐R) score from baseline to Day 14; SECONDARY OUTCOME: Clinical response rate at Day 14;Improvement rate in consciousness‐state classification at Day 14;Changes in EEG features at Day 14;Changes in standardized video‐behavioral indicators at Day 14; INCLUSION CRITERIA: 1. First‐time traumatic brain injury (TBI) in patients aged 18–80 years. 2. Patients diagnosed with internal head injury (Phlegm‐Stasis Blocking Collaterals syndrome) according to Traditional Chinese Medicine (TCM) criteria: (1) History of direct or indirect head trauma; (2) Post‐injury symptoms such as coma, restlessness, dizziness, headache, nausea, and vomiting; (3) Injury location and severity confirmed by history, physical examination, CT, and MRI, referencing the TCM Industry Standard of the People's Republic of China "Diagnostic and Therapeutic Criteria for TCM Diseases and Syndromes" (ZY/T001.1‐94). 3. Disease onset within 1 year, meeting diagnostic criteria for Minimally Conscious State (MCS): following simple commands; answering yes/no via gestures or speech regardless of accuracy; intelligible verbalization; purposeful behavior (including contingent movements and emotional responses to environmental stimuli, distinct from involuntary movements); cle
Epistemonikos ID: 1842fd5178f14aa93fb31aec140d631e51a2538b
First added on: May 02, 2026