A randomized sequential allocation study to determine the ED90 values of initial ropivacaine dose under different temperatures using dural puncture epidural technique for epidural labor analgesia

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: 23? group:All patients received an initial dose of ropivacaine at 23?. The first patient received an initial bolus of ropivacaine (10 mg [0.1%]) combined with sufentanil 0.3 µg/mL in a 10 mL volume;37? group:All patients received an initial dose of ropivacaine at 37?. The first patient received an initial bolus of ropivacaine (10 mg [0.1%]) combined with sufentanil 0.3 µg/mL in a 10 mL volume; CONDITION: Pain during laboring PRIMARY OUTCOME: The ED90s of the initial ropivacaine bolus required for effective analgesia (VAS score <3 within 30 minutes) under dural puncture epidural ; SECONDARY OUTCOME: Visual analogue scale (VAS) score;Bromage score;Apgar score;Adverse event;Delivery related indicators; INCLUSION CRITERIA: 1.Patients aged between 18 and 40 years, experiencing a single full ‐ term pregnancy (including primiparas and multiparas), who are scheduled to receive epidural labor analgesia; 2. Cervical dilation less than 5 cm; Visual Analog Scale (VAS) score greater than 5; 3. American Society of Anesthesiologists (ASA) physical status classification grade II.
Epistemonikos ID: 17ff3550c1ac80c88159b5eef91725ad173ff1d6
First added on: Mar 07, 2026