Study on the Central Mechanism of Acupuncture Modulation of Prefrontal-Amygdala Circuitry Subnetwork in Angina Pectoris based on fMRI-SpDCM

INTERVENTION: Acupuncture group:Select bilateral Neiguan (PC‐6) and Tongli (HT‐5) acupoints and apply acupuncture therapy. Use the Park simulated needle device (Parksham device, PSD) combined with filiform needles, perform lifting, thrusting, rotating, and balanced reinforcing and reducing techniques, and retain the needles for 30 minutes after de qi is achieved.;Sham Acupuncture Group:Select bilateral Neiguan and Tongli acupoints and use sham acupuncture therapy. Use PSD combined with a retractable blunt needle; when the blunt needle contacts the skin, it retracts into the handle without penetrating the skin, without performing needle manipulation, and without achieving deqi, with a retention time of 30 minutes.;Healthy Control Group:not undergo acupuncture treatment.; CONDITION: Angina PRIMARY OUTCOME: Frequency of angina pectoris episodes;Functional Magnetic Resonance Imaging (fMRI); SECONDARY OUTCOME: Visual Analog Scale score;Canadian Cardiovascular Society Angina Grading Criteria grading;Seattle Angina Questionnaire;Anxiety Self‐Rating Scale;Depression Self‐Rating Scale;Transcriptome sequencing;Metabolomics analysis; INCLUSION CRITERIA: 1. Meets the diagnostic criteria for stable coronary artery disease as outlined in the "Guidelines for the Diagnosis and Treatment of Stable Coronary Artery Disease"; 2. Meets the CCS (Canadian Cardiovascular Society) grading criteria for angina severity, Grade I or II; 3. Age between 45 and 65 years (inclusive); 4. Disease duration of at least 3 months, with angina episodes occurring at least twice per week in the past month; 5. At least 2 months of history of standard basic drug therapy prior to enrollment (maintaining the same drugs, dosage, and administration); 6. Good compliance, willing to cooperate with the study, and patient has signed the informed consent form; 7. Right‐handed.