Triple Sleep-promotion Protocol for Delirium Prevention in Intensive Care Patients

Sleep disruption is common among critically ill patients and may contribute to thedevelopment of delirium. Nighttime sleep in the ICU can be disrupted by environmentallight and noise, frequent nursing activities, monitoring, and other clinically necessaryprocedures. Non‐pharmacological strategies that reduce avoidable nighttime disturbancesmay therefore represent a feasible approach to supporting sleep and preventing deliriumwithout adding medication‐related risks.The Triple Sleep‐Promotion Protocol was developed as a multicomponent nursingintervention integrating clustered nighttime nursing care, protected sleep periods, eyemask and earplug use, and pragmatic reduction of avoidable nighttime light and noise. Theprotocol is designed to reduce modifiable sleep disturbances while maintaining routineclinical monitoring and prioritizing patient safety and necessary care at all times.This multicenter randomized controlled trial will examine whether implementation of theTriple Sleep‐Promotion Protocol reduces new‐onset delirium compared with usual ICU care.The study will also evaluate subjective nighttime sleep quality and document interventionadherence and clinically necessary protocol interruptions.