Vacuum-assisted Closure Versus Conventional Dressings in Infected Lower-limb Wounds

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
Wound healing is a complex and dynamic process that includes an immediate sequence ofcell migration leading to repair and closure. Delayed wound healing or non‐healing ofulcers is a significant health problem, particularly in older adults. Vacuum assistedclosure (VAC) is a relatively new technology with applications in a variety of difficultto manage acute and chronic wounds. Literature showed that the outcomes of VAC is abetter than other method. Therefore, this study has been planned. This Randomizedcontrolled trial will be done at Department of General Surgery, Dr Faisal Masood TeachingHospital, Sargodha for 12 months.Sample size of 90 cases; 45 in each groups will beincluded through Non‐probability consecutive sampling and will be randomly divided into 2equal groups. In group A, VAC will be applied to wound. In group B, conventional dressingwill be applied on wound. Wound size after one week will be assessed. If wound will healcompletely, then duration for complete healing will be noted. Success will also be noted.All the data will be recorded in proforma.All the data will be analyzed with SPSS version25. Both groups will be compared by using independent samples t‐test for duration ofhealing, and wound size after a week and chi‐square test for success. P‐value ≤ 0.05 willbe considered as significant. Conclusion and recommendations will be made to obtainbetter results with high success rate, which will lead to better quality of life andearly discharge of patients.
Epistemonikos ID: 158ecbcbd310d379cca80883d1cf343901365241
First added on: Sep 01, 2026