Clinical Trial to Evaluate the Safety of Continuous IV Tirofiban in Acute Ischemic Stroke

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2021
We will recruit men and non-pregnant women of any ethnic background between the age ≥ 18 and ≤ 90 years that have acute ischemic stroke and underwent Mechanical Thrombectomy (MT) with TICI 2b or 2b following MT. These subject\'s will be will be randomized to placebo vs. Tirofiban after consent is obtained. This will be administered via continuous IV starting within 60 minutes of MT procedure completion. At the end of the 24 hour continuous IV dosing period a CT angiography and CT perfusion (CTA/CTP) will be obtained. The rest of the subjects inpatient hospital stay will be done per standard of care. The subject\'s NIHSS and modified Rankin Score (mRS) will be assessed at 90 days.
Epistemonikos ID: 15518d96c4c603a10af222f9cdf912fc77417d53
First added on: Dec 20, 2022