Comparison of Magnesium Sulphate vs Tramadol as Adjuvants in Intrathecal Bupivacaine for Postoperative Pain in TURP Patients

Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2025
The goal of this clinical trial is to determine whether adding magnesium sulfate or tramadol to intrathecal bupivacaine improves postoperative pain control and hemodynamic stability in adult male patients undergoing transurethral resection of the prostate (TURP). The main questions this study aims to answer are: Does the addition of magnesium sulfate or tramadol prolong the duration of postoperative analgesia compared to bupivacaine alone? Does either adjuvant provide better intraoperative hemodynamic stability? Researchers will compare two groups: One group receiving magnesium sulfate plus bupivacaine Another group receiving tramadol plus bupivacaine to see which combination is more effective for pain control and hemodynamic outcomes. Participants will: Receive spinal anesthesia with either magnesium sulfate or tramadol added to bupivacaine. Be monitored during surgery for heart rate, blood pressure, and other vital signs. Be assessed after surgery for pain levels and time until first request for additional pain medication.
Epistemonikos ID: 14d2aa3b387ceafe099bdaa3d1d943f08c483f61
First added on: Aug 12, 2025