Evaluating safety and efficacy of low dose monteplase and nicorandil injected before percutaneous coronary intervention on left ventricular wall motion in patients of acute myocardial infarction:a randomized study.

INTERVENTION: Both Monteplase,15000u per kg,and Nicorandil,4mg bolus injection and 96mg per day continuous injection,are injected. Monteplase but no Nicorandil are injected Nicorandil but no Monteplase are injected Neither Monteplase nor Nicorandil are injected CONDITION: Acute myocardial infarction PRIMARY OUTCOME: Left ventricular wall motion,event of heart failure,death and re‐infarction,bleeding complication,time to recanalization,angiographical data,serum CPK and CKMB SECONDARY OUTCOME: Restenosis of infarcted artery INCLUSION CRITERIA: Acute myocardial infarction within 12 hours from onset.