The effect of Arnebia euchroma ointment on postoperative pain burning and wound healing in hemorrhoidectomy patients

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2020
INTERVENTION: Intervention 1: Intervention group: ARNEBIA Arnebia euchroma plants and roots were purchased from the Sari plant market in northern Iran in February 2017. This plant was kept in the Faculty of Pharmacy, Mazandaran University of Medical Sciences. A. euchroma root was washed and dried in a preheated oven at 40 ???? C for 8 hours. This ointment is made according to the formula of traditional Iranian medicine. Arnebia euchroma ointment is made up of 10% components (10 g of A. euchroma roots, 20 g of goat fat, 15 g of beef butter, 20 g of glycerin and 35 g of Osirine. The weight ratio of Arnebia euchroma ointment was 10% of the original weight. A. euchroma was eaten in a container and heated with beef butter, goat fat and glycerin at 150‐100 ???? C for 30 minutes, then the samples were placed inside the autoclave for 18 minutes at 121 ?? C. The sample was mixed with Osirine, 0.025 g of methyl paraben and 0.015 g of propylene parabens and rubbed for 5 minutes to form a homogeneous ointment. This product was filled in sterile tubes of 50 g and in Was put clean environment. In order to evaluate the stability and concentration ointment formulations them for 2 weeks at 4, 25 and 40 ° C were maintained.After the surgery, the surgeon rubs and bandages two grams of the ointment arnebia in the area of the operation with gas, and this is done every 12 hours to a week by the applicator. As long as the patient is hospitalized, the patient will be guided by the facilitator, and all patients will be instructed on how to do the same twice a day at home and after discharge. Intervention 2: Control group: ousirin .After CONDITION: Hemorrhoidectomy. ; Other diseases of anus and rectum PRIMARY OUTCOME: Burning. Timepoint: After surgery (recovery), 4, 12 and 24 hours after surgery_2 and 4 and 7 days after surgery. Method of measurement: Visual Analogue Scale. PAIN. Timepoint: After surgery (recovery), 4, 12 and 24 hours after surgery_2 and 4 and 7 days after surgery. Method of measurement: Visual Analogue Scale. Wound healing. Timepoint: One week after surgery. Method of measurement: Grade 1 and 2 poor repair, 3 and 4 good repair5 excellent repairs. INCLUSION CRITERIA: People with grade 3 and 4 internal hemorrhoids Be at least 20 years old and at most 60 years old SECONDARY OUTCOME: Defecation. Timepoint: Duration of hospitalization. Method of measurement: The number of times. Diarrhea. Timepoint: Duration of hospitalization. Method of measurement: The number of times. Fear of first defecation. Timepoint: During defecation????? ?????? ??????. Method of measurement: (Visual Analogue Scale). Feeling unwell in the stomach. Timepoint: Duration of hospitalization. Method of measurement: The number of times. Headache. Timepoint: Duration of hospitalization. Method of measurement: yes_no. Itching. Timepoint: Duration of hospitalization. Method of measurement: (Visual Analogue Scale). Nausea. Timepoint: Duration of hospitalization. Method of measurement: The number of times. Received housing. Timepoint: Duration of hospitalization. Method of measurement: Type and volume of medication. Urine. Timepoint: Duration of hospitalization. Method of measurement: The number of times. Vomit. Timepoint: Duration of hospitalization. Method of measurement: The number of times.
Epistemonikos ID: 13d90d44b8c5cef2cf29510289108f393b881326
First added on: Apr 22, 2021