Atorvastatin in Major Depressive Disorder

INTERVENTION: Intervention 1: Intervention group: in this group sertralin(sobhan pharmaceutical company)with a final up to 100 mg and atorvastatin 20mg once a day and during 8 weeks are prescribed. Intervention 2: Control group: in this group sertralin(sobhan pharmaceutical company)with a final up to 100 mg and placebo with the same shape,size,color and taste as a atorvastatin prescribeed once a day. CONDITION: F33.0 Major Depressive Disorder. ; Major depressive disorder, recurrent, mild PRIMARY OUTCOME: Depression severity score in Hamilton Rating Scale for depression. Timepoint: Before intervention and 4, 8 weeks after intervention. Method of measurement: Hamilton Rating Scale And DSM5 Criteria. SECONDARY OUTCOME: Depression severity score in Hamilton Rating Scale for depression. Timepoint: Before intervention and 4,8 weeks after intervention. Method of measurement: Hamilton Rating Scale for depression. INCLUSION CRITERIA: ? Age 20 to 55 years ? People with Major depressive disorder based on DSM‐5 Criteria and clinical interview ? Lack of obvious and serious medical illness based on medical history, medications used, and history of hospitalization in a clinical interview ? Use of any agent or drugs that may have any interactions with sertralin or atorvastatin pharmacokineticlly or pharmacodinamiclly. ? Absence of active suicidal thoughts ? Absence of psychotic symptoms ? No symptoms of severe anxiety or panic disorder based on history and patients self report ? Having Hamilton rating scale for depression above 7 at the beginning of treatment