Effectiveness of ice pack and hot pack on the snakebite site

INTERVENTION: E02.258 E02.565 The study has 3 arms with 30 patients each being randomly randomized by draw, controlled, parallel. The first arm will be the control group (no compress), the second arm will be the ice pack group and the third arm will be the hot pack group. The compress will be applied to the site of poisoning for 3 consecutive days of 12/12 hours for a period of 20 minutes. All patient groups will receive standard antivenom treatment and institutional protocol for medications and envenomation evaluation. There will be no masking, it will be an open study. CONDITION: Snakebite PRIMARY OUTCOME: It is expected that the group that used the ice pack is more effective for the treatment of pain than the group that used hot or the control group. SECONDARY OUTCOME: Secondary outcomes are not expected. INCLUSION CRITERIA: Patients of both sexes with Bothropic snake envenomation within a maximum of 24 hours of evolution; age greater than 18 years