Helicobacter pylori eradication - which is the best regimen: classic triple therapy or sequential therapy?

INTERVENTION: 100 peptic ulcer or functional dyspepsia patients randomized to two eradication regimens ‐ two arms Helicobacter pylori eradication study: 1. Amoxicillin + clarithromycin + lansoprazole for 10 days 2. Amoxicillin + lanzoprazole 5 days, followed by clarithromycin + tinidazole + lansoprazole 5 days Route of administration: Oral The pills are packed in blisters and the control is done by counting of the pills from one of the investigators. CONDITION: Epigastric pain with normal or altered endoscopy ; Digestive System PRIMARY OUTCOME: 1. Eradication rates; 2. Cure rates will be achieved by endoscopy or UBT performed two months after the end of the treatment SECONDARY OUTCOME: Adverse effects are assessed by a questionnaire at the final visit INCLUSION CRITERIA: 1. Outpatients with organic or functional dyspepsia 2. Aged between 18 and 80 years 3. Helicobacter pylori diagnosis confirmed by histology, rapid urease test or urea breath test (UBT) 4. No previous eradication history 5. Patients need to sign and understand the informed consent term