Clinical study of bio-amnion implantation in conjunctive flap used in glaucoma trabeculectomy

• Aim: To observe the effect of different implantation position of bio-amnion used in glaucoma trabeculectomy through filtrative bleb and intraocular pressure. • Methods: Forty-five eyes of glaucoma were randomly divided into 3 groups. In group A, biological amnion was implanted in 15 eyes under conjunctive flap; In group B, biological amnion was implanted in 15 eyes under scleral flap. Group C was as control group. We observed the effect of intraocular pressure, filtrative bleb and complications. • Results: The average intraocular pressure in group A was about 11.80-21.22mmHg during 6 months follow-up, 12.48-21.52mmHg in group B, and 10.60-28.48mmHg in group C. Conditional successful rate of group A, B and C was 93.3%, 86.7%, 66.7% respectively. • Conclusion: Bio-amnion implantation improves effectively the rate of success in glaucoma trabeculectomy. The operation of bio-amnion implantation position used in conjunctive flap is simple and has a conditional successful rate compared with other groups, which reinforce conjunctive flap and prevent frail filtrative bleb.