Role of homoeopathic medicines on immunity in leprosy

INTERVENTION: Intervention1: Mercurius solubilis ,Sulphur,Natrum Muraticum: 200 potency for one year Intervention2: Multi Drug Therapy (Rifampicin, Dapson,Clofamazine): WHO recomended dose and schedule Control Intervention1: Multi Drug Therapy (Rifampicin, Dapson,Clofamazine): As per WHO recomended schedule CONDITION: leprosy PRIMARY OUTCOME: In vitro assays of interleukins (IFNy, TNFa,IL‐4, IL‐10 ) in the peripheral blood , 10. Estimation of interlieukins like IFNy, TNFa IL2, IL4, IL10 of M. leprae antigen stimulated PBMC at different stages‐‐‐‐‐‐Timepoint: two years SECONDARY OUTCOME: Complete regain of sensation,regain of normal skin colour, regain of normalcy from psychological depression‐‐‐‐‐‐Timepoint: Three years INCLUSION CRITERIA: Proven cases of ladult male and female eprosy patient between the age group from 18 to 60 years who have had no previous history of treatment will be taken in the study.