Assessment of immunocompetence by the intake of Lactobacillus plantarum HOKKAIDO contained yogurt

INTERVENTION: Intake 90 g of yogurt containing Lactobacillus plantarum HOKKAIDO daily for 8 weeks. Intake 90 g of yogurt daily for 8 weeks. Intake 90 g of yogurt‐like non‐fermented products daily for 8 weeks. CONDITION: Low immune system PRIMARY OUTCOME: NK cell activity SECONDARY OUTCOME: Five fraction of leukocyte, IgG, IgE, IgM, IL‐1, IL‐4, IL‐6, IL‐8, IL‐10, IL‐12, T‐Cho, LDL‐Cho, HDL‐Cho, TG, FBG, HbA1c, 25‐OHD, MIF INCLUSION CRITERIA: 1.Subjects who show relatively low NK cell activity 2.Subjects who agree to participate in the current study with written informed consent