Effects of extract of decaffeinated green coffee beans on postprandial serum glucose in healthy subjects.

INTERVENTION: 1) A total of 41 subjects (22 men and 19 women ) without type 2 diabetes were enrolled in the present study. 2) Test meals of 200g of a carbohydrate‐rich meal plus placebo (200ml) were administered in a double‐blind trial. 3) Antecubital venous blood was collected before the meal and at t = 0.5, 1, 1.5 and 2 h, where t = 0 was the start of test meal ingestion. 1) A total of 41 subjects (22 men and 19 women ) without type 2 diabetes were enrolled in the present study. 2) Test meals of 200g of a carbohydrate‐rich meal plus extract of decaffeinated green coffee beans (100mg/200ml water) were administered in a double‐blind trial. 3) Antecubital venous blood was collected before the meal and at t = 0.5, 1, 1.5 and 2 h, where t = 0 was the start of test meal ingestion. 1) A total of 41 subjects ( 22 men and 19 women ) without type 2 diabetes were enrolled in the present study. 2) Test meals of 200g of a carbohydrate‐rich meal plus extract of decaffeinated green coffee beans (300mg/200ml water) were administered in a double‐blind trial. 3) Antecubital venous blood was collected before the meal and at t = 0.5, 1, 1.5 and 2 h, where t = 0 was the start of test meal ingestion. CONDITION: hyperglycemia PRIMARY OUTCOME: 1) Postprandial serum glucose (0,30,60,90, and 120min) and AUC (0‐120min); 2) Postprandial serum insulin (0,30,60,90, and 120min) and AUC (0‐120min) INCLUSION CRITERIA: 1) Healthy men and women over 20 years old and under 50 years old. 2) Individuals who can abstain from before the experiment. 3) Individuals who understand the purpose and contents of the experiment. 4) Individuals to be suitable by the doctor.