Effect of fructose in muffins on short term and long term glucose and lipid control

INTERVENTION: 2 X80g high fat muffins (30% fat) containing 21g sucrose per muffin then 2 X80g high fat muffins (30% fat) containing 21g fructose per muffin (in random order one week apart) in 2 acute studies (3 hour study with blood samples taken at baseline, 30,60.90,120,150 and 180 minutes) immediately followed by 4 weeks of 2 X80g low fat muffins (15% fat)/daily containing 21g fructose per muffin followed immediately by a repeat of the two acute studies. Compliance assessed by checklist and frozen muffin return. CONDITION: Type 2 diabetes PRIMARY OUTCOME: Triglyceride level by serum assay SECONDARY OUTCOME: Body Weight as measured in the clinic by the clinic staff Glucose by serum assay INCLUSION CRITERIA: Overweight or obese BMI>25