A study comparing two medicines to help adult patients regain muscle strength after keyhole surgery

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Low Dose Sugammade XWith Neostigmine and Glycopyrrolate: WILL Receive an Intravenous Low Dose Sugammade XCombined With Neostigmine and Glycopyrrolate Control Intervention1: Neostigmine with Glycopyrrolate Alone: Will Receive an Intravenous injection Neostigmine and Glycopyrrolate alone CONDITION: Health Condition 1: R299‐ Unspecified symptoms and signs involving the nervous and musculoskeletal systems PRIMARY OUTCOME: Time required to achieve a Train of Four ratio greater than 0.9 after administration of the reversal agent that is measured from drug administration until quantitative TOF ratio exceeds 0.9Timepoint: Time required to achieve a Train of Four ratio greater than 0.9 after administration of the reversal agent that is measured from drug administration until quantitative TOF ratio exceeds 0.9 SECONDARY OUTCOME: 1.Incidence of residual neuromuscular blockade in the postoperative period that is TOF ratio less than 0.9. ; 2.Time to tracheal extubation after administration of reversal agents. ; 3.Time to achieve PACU discharge readiness e.g, modified Aldrete score greater than or equal to 9. ; 4.Hemodynamic changes that is heart rate and blood pressure after reversal. ; 5.Incidence of adverse effects ; a.Bradycardia ; b.Tabchycardia ; 6.Postoperative nausea and vomiting ; 7.Hypersensitivity reactionsTimepoint: 1.From administration of reversal agent until extubation that is in minutes. ; 2.From reversal administration until extubation ; INCLUSION CRITERIA: 1.Adult patients aged 18 to 60 years. 2.ASA physical status 1 to 3. 3.BMI less than 36 kg per m2. 4.A Train of Four count of 1 to 3 at the end of surgery. 5.Adult undergoing laparoscopic surgeries.
Epistemonikos ID: 07475d79ce2281171a89608130a6700d40d72f3f
First added on: Oct 08, 2026