A Study on the effect of a single dose of Dexamethasone injection in reducing pain and nausea after cesarean section under spinal anesthesia

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Dexamethasone: Patients undergoing caesarean section under spinal anesthesia will receive Dexamethasone 8 mg(2ml) stat dose after the delivery of the baby and cord clamping. And will be monitored for postoperative analgesia till 15 hours post operatively , post operative nausea and vomiting till 24 hours postoperatively and postoperative blood sugar level at 0 , 6 and 24 hours postoperatively. Control Intervention1: Placebo: Patients undergoing caesarean section under spinal anesthesia will receive either placebo (NS 2 ml) CONDITION: Health Condition 1: O00‐O9A‐ Pregnancy, childbirth and the puerperium PRIMARY OUTCOME: The addition of 8 mg Dexamethasone as an adjuvant is expected to provide superior postoperative analgesia following following lower segment caesarean section compared with placeboTimepoint: VAS score will be assessed after 30 minutes of skin closure,1 hour of skin closure and then every 1 hour upto 8 hours after skin closure then at 12 th and 15 th hour after the skin closure or upto the first rescue analgesic is given SECONDARY OUTCOME: The addition of 8 mg Dexamethasone as an adjuvant is expected to releive post operative nausea and vomiting following following lower segment caesarean section compared with placebo ; ; ; The addition of 8 mg Dexamethasone as an adjuvant might increase blood glucose levels following lower segment caesarean section compared with placeboTimepoint: 1. Incidence of postoperative nausea and vomiting during the study period upto 24 hours ; ; 2.blood glucose monitoring at 0 ,6 and 24 hours postoperative ; INCLUSION CRITERIA: ASA Physical Status II patients. .Age between 18 and 45 years. .Patients undergoing lower segment cesarean section under spinal anesthesia. .Patients willing to participate and provide written informed consent.
Epistemonikos ID: 06e8ea7eb06f72736b31ec029ca519e3fbdaf8d5
First added on: Oct 08, 2026