Psychoanalytic therapy (PT) and cognitive-behavioral therapy (CBT) in outpatients with anxiety (panic disorder/agoraphobia) and comorbid personality disorders.

INTERVENTION: Participants will be randomised into one of the two arms: 1. Psychoanalytic therapy (PT) 2. Cognitive‐behavior therapy (CBT) They will be assessed at the study centrebefore treatment, after termination of treatment and at a 6‐year follow‐up. Additional self‐report questionnaire and LIFE‐Interviews once a year. CONDITION: Panic disorder, Agoraphobia, Personality disorder ; Mental and Behavioural Disorders PRIMARY OUTCOME: Primary outcome measure as of 23/05/2016:; 1. Overall symptomatic burden according to LIFE‐interview over the 6 year follow‐up‐period ; 2. Individual change in patients self‐reports (combination symptomatic burden, SCL‐90‐GSI, interpersonal problems, IIP, and life satisfaction, FLZ) between beginning of treatment and 6‐year‐follow‐up; ; Original primary outcome measures:; 1. Individual change in mental disorders (according to SCID‐Interviews, Axis I and Axis II) between beginning of treatment and 6‐year‐follow‐up ; 2. Individual change in patients self‐reports (combination symptomatic burden, SCL‐90‐GSI, interpersonal problems, IIP, and life satisfaction, FLZ) between beginning of treatment and 6‐year‐follow‐up SECONDARY OUTCOME: Secondary outcome measure as of 23/05/2016:; 1. Individual change in criteria for personality disorders (according to SCID‐interview, axis II); 2. Patients Health Questionnaire (PHQ); 3. Assessment of DSM‐IV Personality Disorders (ADP‐IV); 4. Panik‐ und Agoraphobieskala (PAS); 5. Experiences in Close Relationships ‐ Revised? (ECR); 6. ?Structural Impairment?, assessed with: Inventory of Personality Organization ? short form (IPO‐16), Operationalized Psychodynamic Diagnostics (OPD), and Scales of Psychological Capacities (SPC); 7. Short Form Health Survey (SF‐12); 8. Willingness‐to‐pay (WTP); ; Original secondary outcome measures:; 1. Overall symptomatic burden according to LIFE over the 6 year follow‐up‐period; 2. Patients Health Questionnaire (PHQ); 3. Assessment of DSM‐IV Personality Disorders (ADP‐IV); 4. Panik‐ und Agoraphobieskala (PAS); 5. Experiences in Close Relationships ‐ Revised? (ECR); 6. ?Structural Impairment?, assessed with: Inventory of Personality Organization ? short form (IPO‐16), Operationalized Psychodynamic Diagnostics (OPD), and Scales of Psychological Capacities (SPC); 7. Short Form Health Survey (SF‐12); 8. Willingness‐to‐pay (WTP) INCLUSION CRITERIA: 1. Panic disorder (including partial remission, i.e., maximally 2 months without significant symptoms) and/or agoraphobia plus: 2. At least one of the following PDs: avoidant PD, dependent PD, obsessive‐compulsive PD, depressive PD, negativistic PD, histrionic PD, borderline PD without acute suicidality, narcissistic PD, PD not otherwise specified (i.e., in at least two of the PD categories listed above only 1 criterion is missing to fulfill the diagnosis) 3. Age: at least 21 years