Effects of Music Therapy on Stress During Orthodontic Mini-screw Placement

This randomized clinical trial evaluated acute stress responses during orthodonticmini‐screw placement and whether listening to music during the procedure influenced theseresponses. Thirty‐two participants aged 14 to 20 years who were undergoing mini‐screwplacement for the first time were randomly assigned in equal numbers to a musicintervention group or a control group receiving the same orthodontic procedure withoutmusic. Saliva samples were collected immediately before and after the procedure tomeasure salivary cortisol and alpha‐amylase. Pulse rate, systolic and diastolic bloodpressure, body temperature, and oxygen saturation were also measured at the same timepoints. The study was designed to determine whether mini‐screw placement produced ameasurable acute stress response and whether music influenced biochemical andphysiological changes associated with the procedure.