A clinical trial to compare the effects of Misoprostol(per rectal) and Oxytocin(intravenous infusion)in reducing blood loss in women undergoing caesarean section

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2009
INTERVENTION: Intervention1: Misoprostol is given rectally after peritonium is opened during LSCS.: Dose of Misoprostol‐800 microgram. Control Intervention1: Oxytocin infusion started immidiately after delivery of the newborn.: Dose of Oxytocin‐10 units in 500 ml of Ringer Lactate solution. CONDITION: Healthy women without known risk factor for Postpartum Haemorrhage are studied. PRIMARY OUTCOME: blood loss during operation and 8 hours postpartum and change in the hemoglobin 24 hours after delivery.‐‐‐‐‐‐Timepoint: Blood loss:during operation and upto 8 hours postpartum. ; Hb :predelivery and 24 hours after delivery. SECONDARY OUTCOME: need for additional uterotonic, incidence of side effects and complications, need for blood transfusion and cost of oxytocic.‐‐‐‐‐‐Timepoint: Upto 24 hours postpartum. INCLUSION CRITERIA: women undergoing elective or emergency caesarean section.
Epistemonikos ID: 06453237e39e9bbc9d8d1aa2c9e628f79411cce4
First added on: Aug 22, 2024