A Study of Macitentan, in Healthy Japanese Male Participants

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2020
The main purpose of this study is to evaluate the safety and tolerability after multiple-dose administrations of macitentan with titration regimen starting from Dose 1 once daily (qd) up to Dose 2 qd in Japanese healthy adult male participants (Part 1) and to evaluate the effect of food on pharmacokinetics of macitentan and its active metabolite (ACT-132577) in Japanese healthy adult male participants with macitentan Dose 3 tablet (Part 2).
Epistemonikos ID: 064321095b0721928f0c9f4418207e1108c2cb66
First added on: May 07, 2024