Effect of Bromelain , Curcumin and Epigallocatechin in the treatment of outpatient Covid-19 patients

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2021
INTERVENTION: Intervention 1: Intervention group: The group receiving 2 drug capsules In addition to standard treatments ( each capsule containing 150 mg Bromelain, 300 mg Curcumin and 50 mg Epigallocatechin ) daily at intervals of 12 hours during the day for 5 days. Intervention 2: Control group: The group receiving the 2 placebo capsules in addition to standard treatments daily at intervals of 12 hours during the day for 5 days. CONDITION: Covid 19. ; Pneumonia due to SARS‐associated coronavirus J12.81 PRIMARY OUTCOME: Body temperature. Timepoint: Up to two weeks after intervention. Method of measurement: Thermometer. Cough severity. Timepoint: Up to two weeks after intervention. Method of measurement: Clinical manifestations of the patient with a score of 1 to 10 depending on the cough severity. Fatigue. Timepoint: Up to two weeks after intervention. Method of measurement: Phone call, or visit by person in cases of symptom aggravation. Gastrointestinal symptoms. Timepoint: Up to two weeks after intervention. Method of measurement: Phone call, or visit by person in cases of symptom aggravation. Myalgia. Timepoint: Up to two weeks after intervention. Method of measurement: Phone call, or visit by person in cases of symptom aggravation. Oxygen saturation. Timepoint: Up to two weeks after intervention. Method of measurement: Pulse oximetery. Sense of smell. Timepoint: Up to two weeks after intervention. Method of measurement: Phone call, or visit by person in cases of symptom aggravation. Sense of taste. Timepoint: Up to two weeks after intervention. Method of measurement: Phone call, or visit by person in cases of symptom aggravation. SECONDARY OUTCOME: Hospitalization. Timepoint: Up to one month after intervention. Method of measurement: Phone call, and clinical follow up. Lung involvement. Timepoint: Up to two weeks after intervention. Method of measurement: Phone call, and clinical follow up. Mortality. Timepoint: Up to one month after intervention. Method of measurement: Phone call, and clinical follow up. INCLUSION CRITERIA: New 2019 Corona‐virus infection (COVID‐19) confirmed by rt‐PCR test referred to an outpatient clinic Aged over 18 years
Epistemonikos ID: 058aef347c7f141ef42f836f1fa9e019f1908ee7
First added on: Sep 13, 2021