A randomised controlled blinded trial to investigate the effect of hyoscine butylbromide during colonoscopy on rates of polyp detection.

INTERVENTION: During the isolated procedure of a single colonoscopy using the standard equipment, monitoring and sedation; the intervention (a single dose of hyoscine butylbromide 20 mg intravenously over approximately 10 seconds, also commercially known as buscopan) will be administered upon intubation of the caecum. CONDITION: Colonic polyposis PRIMARY OUTCOME: Number of colonic polyps detected by inspection of the bowel via a fibreoptic colonoscope in patients with polyps detected at the isolated single procedure of colonoscopy. SECONDARY OUTCOME: Average number of polyps detected by inspection of the bowel with a fibreoptic colonoscope during the isolated single procedure of colonoscopy. Number of patients with polyps detected by inspection of the bowel with a fibreoptic colonoscope during the isolated single procedure of colonoscopy. INCLUSION CRITERIA: Booking for colonoscopy. Intact colon (no previous colonic resection).