Assessment of the effect of nanocurcumin supplement in patients with COVID-19

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2020
INTERVENTION: Intervention 1: Intervention group: People in the intervention group will receive nanocurcumin supplement at a dose of 160 mg per day for 6 days. Curcumin is a natural polyphenolic antioxidant responsible for the turmeric yellow color. Nanocurcumin supplements are produced in the form of 40 mg capsules by Exir Nano Sina Company, and patients will receive 4 supplements orally (every 12 hours 2 capsules) for 6 days in addition to the routine treatment,. Intervention 2: Control group: People in the control group are given placebo capsules that are completely similar to nanocurcumin supplements in terms of shape and color and are asked to take 4 placebo capsules daily (every 12 hours 2 capsules) for 6 days. CONDITION: COVID‐19. ; Coronavirus infection, unspecified U07.1 PRIMARY OUTCOME: Hs‐CRP. Timepoint: Before and after 6 days of supplementation. Method of measurement: ELISA. Percentage of recovery. Timepoint: Before and after 6 days of supplementation. Method of measurement: CT scan of the lungs. SECONDARY OUTCOME: Complete Blood Count. Timepoint: Before and after 6 days of supplementation. Method of measurement: Automated cell count. Percentage of oxygen saturation. Timepoint: Before the intervention and then daily until discharge. Method of measurement: Pulse oximeter. Severity of infection symptoms of upper and lower respiratory tract. Timepoint: Before the intervention and then daily during the supplementation period. Method of measurement: Questionnaire. INCLUSION CRITERIA: Confirmation of Covid‐19 by positive PCR test or lung scan Admission to hospital Corona wards other than ICU Filling out the informed consent form by the patient or the patient's first‐degree relatives
Epistemonikos ID: 055638123120f108c38e908a3511e6953750e0f9
First added on: Oct 04, 2020