N-[4-(1,1'-biphenyl)methyl]-4-(4-thiomorpholinylmethyl) benzenamines as non-oxazolidinone analogues of antimycobacterial U-100480.

Category Primary study
JournalBioorganic & medicinal chemistry letters
Year 1998
Thiomorpholine analogues of U-100480 with the biphenylmethyl group replacing the acetamidomethyloxazolidinone moiety have been synthesized and tested as antimycobacterial agents together with various related derivatives. Some biphenyl derivatives were endowed with high activity against Mycobacterium tuberculosis and other non-tuberculous mycobacteria.
Epistemonikos ID: 04e5b3548d7213b7ab0ba0c1cac1b6e227762235
First added on: Nov 14, 2024