EFFICACY OF 38% SILVER DIAMINE FLUORIDE FOR ARRESTING CARIES IN PERMANENT MOLARS OF CHILDREN AND ADOLESCENTS: A RANDOMIZED CLINICAL TRIAL

INTERVENTION: 1 minute of 38% Silver diamine fluoride application,3 minutes of 38% Silver diamine fluoride application 38% Silver Diamine Fluoride (SDF) is a topical antimicrobial and remineralizing agent which was cleared by the FDA as a Class II medical device to treat tooth sensitivity. In certain circumstances, SDF may be used as a non‐restorative treatment to arrest carious lesions on primary and permanent teeth. In arm 1 of the study the study 38% SDF will be applied for 1 minutes on permanent molars.,38% Silver Diamine Fluoride (SDF) is a topical antimicrobial and remineralizing agent which was cleared by the FDA as a Class II medical device to treat tooth sensitivity. In certain circumstances, SDF may be used as a non‐restorative treatment to arrest carious lesions on primary and permanent teeth. In arm 2 of the study 38% SDF will be applied for 3 minutes on permanent molars. Active Comparator Drug,Active Comparator Drug CONDITION: Silver diamine fluoride, 38% Silver diamine fluoride, SDF, arresting caries, permanent molars, children, adolescents Untreated dental caries, which are cavitated dentin carious lesions in the permanent molars of children and adolescents without a history of pulpal infection, are studied for arrest rates using silver diamine fluoride. are healthy and cooperative during dental procedures and have written consent from parents and verbal consent from participants. The study will be performed in permanent molars that have untreated dentine carious lesions, ICDAS 5 or ICDAS 6. ; Silver diamine fluoride, 38% Silver diamine fluoride, SDF, arresting caries, permanent molars, children, adolescents PRIMARY OUTCOME: Arrested caries 3, 6, 12, 18 and 24 months after the first application Arrested rate SECONDARY OUTCOME: Factors affect caries arrested rate 3, 6, 12, 18 and 24 months after the first application Questionnaire, examination and statistical analysis INCLUSION CRITERIA: Participant INCLUSION CRITERIA: 1. Patients should be from kindergarten 3 to grade 7 in secondary school. 2. Patients should have caries lesions in at least one untreated permanent molar. 3. Patients should be in good health. 4. Patients should be cooperative during dental procedures. 5. Patients should have written consent from their parents or guardians. 6. Patients should provide verbal consent. Teeth INCLUSION CRITERIA: 1. The teeth should be permanent molars. 2. The teeth should have untreated caries lesions. 3. The teeth should have ICDAS 5 or ICDAS 6 caries lesions.