Does Metformin potentiate the effect of Rosuvastatin therapy on biochemical markers in Patients with Polycystic Ovary Syndrome?

Category Primary study
Registry of TrialsANZCTR
Year 2012
INTERVENTION: The total number of groups is 2. group 1 and group 2 take resuvastatin 10 mg once daily only for 3 months. starting with the fourth month and for 3 months (till the 6th month included), group 1 takes metformin (850 mg twice a day) along with resuvastatin; while group 2 takes placebo pills (microcellullose capsules) in addition to resuvavstatin. All medications are oral tablets CONDITION: Polycystic ovary syndrome (PCOS) PRIMARY OUTCOME: change in inflammatory markers in PCOS patients on Resuvastatin if Metformin is added. this is tested by serum assay every 3 months SECONDARY OUTCOME: menstrual irregularities are assessed every month where the patients keep daily menstrual diary to report it every month. INCLUSION CRITERIA: adult females aged 18‐55, diagnosed as having PCOS, not planning to conceive
Epistemonikos ID: 040c25d598d287be396ae08c0c105401c0cc1cf4
First added on: Aug 22, 2024