Clinical Efficacy of Piracetam on the Treatment of Breath _Holding Spells

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2020
INTERVENTION: contorol group: administration of placebo in 2 mounth period Intervention 1: Intervention group: administration of piracetam in 2 mounth period with dose of 40/mg/kg/day. Intervention 2: contorol group: administration of placebo in 2 mounth period. Intervention group: administration of piracetam in 2 mounth period with dose of 40/mg/kg/day Placebo Treatment ‐ Drugs CONDITION: Breath‐holding spells. ; Other and unspecified abnormalities of breathing Other and unspecified abnormalities of breathing PRIMARY OUTCOME: The number of Breath‐holding spell. Timepoint: before prevention and 2 weeks after prevention. Method of measurement: questionarie of parents. INCLUSION CRITERIA: INCLUSION CRITERIA: 1) History of breath‐ Holding spell and physical and neurological examination by pediatric neurologist. 2) Minimum age 6 month and maximum 3 years old 3) Normal EEG 4) absent of systematic disease 5) Normal growth and Development 6) No history of epilepsy in family member 7) No Electrolyte Abnormality (Hypoglycemia and Hypocalcaemia ) Exclusion criteria: 1) Children with history of convulsion 2) Children that received Anticonvulsant drugs. 3) Delayed neurotic development 4) all Children with heart diseases 5) all children with anemia 6) Side effects of priacetam including true dizziness, convulsion, extra pyramidal sings, lethargy, headache, sleepy; gastrointestinal complication including nausea and vomiting, diarrhea, constipation, anorexia, increased weight
Epistemonikos ID: 036633ef8712c0c2b04b9a4654fc75144326929d
First added on: Apr 22, 2021