Spontaneus productions of interleukins in patients with the first diagnosed pulmonary tuberculosis.

The authors showed in the article an analysis related to the level of spontaneous products of IL-1, IL-2, IL-4, IL-6, IL-12, gamma-IFN in blood serum of patients with first diagnosed pulmonary tuberculosis in comparison with healthy donors who have a negative and hyper reaction to a Mantous skin test. It was found out the decrease in the level of gamma-IFN in patients with tuberculosis of lungs and healthy patients with a hyper reaction to a Mantous skin test. The lowest production of IL-1 was found out in patients with local tuberculosis, the greatest - in patients with infiltrative lung tuberculosis. The authors have not found out dependence of the level of probed interleukin on the form of tuberculosis process in lungs.