Amnio infusion in preterm premature rupture of membranes

INTERVENTION: Randomised controlled trial. Women with very early premature rupture of membranes will be randomised into (a) expectant management or (b) serial amnioinfusions. CONDITION: Pregnancy and Childbirth: Preterm premature rupture of membranes ; Pregnancy and Childbirth ; Preterm premature rupture of membranes PRIMARY OUTCOME: The study will compare the neonatal, maternal and pregnancy outcomes in pregnancies with very early PROM managed expectantly with those managed with serial amnioinfusions (replacement of fluid into the amniotic sac). SECONDARY OUTCOME: Not provided at time of registration INCLUSION CRITERIA: 15 women with premature rupture of membranes in each arm