The case-control study of relationship between ribavirin therapy and bradycardia in SARS patients

Authors
Category Primary study
JournalAdverse Drug Reactions Journal
Year 2004
Objective: To investigate whether bradycardia is related with ribavirin treatment in SARS patients. Methods: 181 cases with SARS were retrospectively enrolled and divided into two groups in this case-control study, that is, ribavirin group (ribavirin and basic therapy) and control group (basic therapy only). Results: Compared with control group, ribavirin therapy decreased the SARS patients' heart rate (p 0.05) at 0-3 days and OR was 4.1(1.59-10.55). Conclusion: When given by intravenous infusion, ribavirin caused a dose-related bradycardia in SARS patients.
Epistemonikos ID: 0093bbdbb6c6d90486a97a32251ad30444463612
First added on: Jun 03, 2020