estudio de observación de la eficacia de la olanzapina MECT combinada en el tratamiento de la esquizofrenia refractaria

OBJECTIVE: To observe the MECT (MECT) combined with olanzapine treatment of refractory schizophrenia. METHODS: 84 cases of refractory schizophrenia were randomly divided into observation group and control group 42 cases. The control group was treated with olanzapine treatment, observation group MECT combined with olanzapine treatment. To compare the two groups total effective, positive symptoms and negative syndrome scale (PANSS), symptom scale (TESS) scores and adverse reactions during treatment. Results: The total efficiency of 95.2%, 69.0% higher than the very significant (P <0.01). 2,4,6,8 weeks after treatment, both groups PANSS total score, positive symptoms, negative symptoms and general pathology scores were significantly or very significantly lower than before treatment (P <0.05, P <0.01); treatment 4,6 eight weeks later, the observation group positive symptoms scores was significantly or very significantly lower than the control group (P <0.05, P <0.01); after 6,8 weeks of treatment, the observation group general pathology scores were significantly lower than the control group (P < 0.05). TESS scores of the two groups and adverse reactions, the difference was not significant (P> 0.05). CONCLUSION: MECT combined with olanzapine in the treatment of refractory schizophrenia effective than olanzapine alone.